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Webinar – PKBOIN-12 and Project Optimus: Identifying the Optimal Biological Dose

Webinar – Physiologically-Based Pharmacokinetics (PBPK) Modeling and Simulation: A Transformative Tool for Early-Stage Clinical Development

Webinar – Oncology Drug Development under Project Optimus: Case Studies

Exploring Basket Trials in Oncology Drug Development: Enhancing Precision with Bayesian Methods

Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. Yap C, Rekowski J, Ursino M, Solovyeva O, Patel D, Dimairo M, Weir CJ, Chan AW, Jaki T, Mander A, Evans TRJ, Peck R, Hayward KS, Calvert M, Rantell KR, Lee S, Kightley A, Hopewell S, Ashby D, Garrett-Mayer E, Isaacs J, Golub R, Kholmanskikh O, Richards DP, Boix O, Matcham J, Seymour L, Ivy SP, Marshall LV, Hommais A, Liu R, Tanaka Y, Berlin J, Espinasse A, de Bono J., BMJ. 2023