Moving to Agile: A New Approach to Statistical Programming


June 12, 2025

Prior to recent advances, traditional software development processes have been characterized by rigid methods that required teams to follow pre-defined processes. However, the advent of Agile programming revolutionized traditional development processes by shifting the focus to flexibility, collaboration, and continuous improvement. Unlike traditional methods, Agile embraces change and enables teams to respond quickly to new requirements.

Now, the Agile approach has moved from software development into statistical programming, allowing teams to work in small increments rather than following a linear, pre-planned process. Instead of extensive upfront planning, Agile encourages adaptability and frequent reassessment of project goals.

Here, I discuss Agile methodologies, the benefits and challenges, and invite readers to learn more with our new case study on implementing Agile and Scrum for SAS programming in clinical development.

 

What is Agile programming?

Agile is an iterative project management and development approach that prioritizes flexibility, collaboration, and responsiveness to change. Though originally developed for software engineering, Agile has since gained widespread adoption across various industries, including healthcare and clinical research.

At the heart of Agile is the concept of breaking down complex projects into smaller, manageable units of work, called “sprints,” typically lasting one to four weeks. At the end of each sprint, the team delivers a functional product increment, ensuring continuous feedback and the ability to adjust course as needed.

Key tenets of Agile in statistical programming include:

  • Prioritizing individuals and interactions over processes and tools to foster teamwork and effective communication.
  • Prioritizing customer collaboration over contract negotiation to involve stakeholders throughout the process.
  • Prioritizing responding to change over following a plan to support remaining flexible to evolving needs.

These tenets support incremental delivery of outputs, frequent feedback loops to all programmers, and overall team collaboration.

 

Benefits of Agile programming

Agile methodologies offer numerous additional advantages, making them a preferred choice for modern development teams:

 

Faster delivery times

Agile focuses on small, manageable iterations (sprints), allowing teams to release interim deliverables frequently rather than waiting for the entire product to be complete.

 

Higher customer satisfaction

Continuous delivery and ongoing stakeholder involvement ensure products align with user needs, leading to better adoption and positive feedback.

 

Reduced risk of project failure

By regularly assessing project goals, teams can detect potential issues early and make adjustments before they become costly problems.

 

Agile methodologies

Agile methodologies come in different flavors, each tailored to unique team dynamics and project needs.

 

Scrum

Scrum is one of the most widely used Agile frameworks. It divides development into short cycles called sprints (typically 2 weeks), during which teams work on prioritized tasks. Scrum incorporates daily stand-up meetings and reviews to track progress and remove obstacles.

 

Kanban

Kanban is a visual workflow management system that emphasizes continuous delivery. Teams use a Kanban board to track tasks in various stages (To-Do, In Progress, Completed), ensuring transparency and limiting work in progress to prevent bottlenecks.

 

XP

XP focuses on high-quality development practices like test-driven development (TDD) and continuous integration (CI). It encourages pair programming and frequent code reviews to enhance software quality.

 

Challenges to adopting Agile

While Agile offers many benefits, teams may face challenges when adopting Agile practices. Rapid development cycles can lead to frequent scope changes, making it hard to maintain focus. This can be avoided by clearly defining priorities and using backlog refinement sessions to keep scope manageable.

Additionally, Agile relies heavily on collaboration, but without proper communication, misunderstandings can arise. Strategies for preventing this include encouraging daily stand-ups, using standard project management tools, and fostering a culture in which open commentary is encouraged.

Finally, transitioning to Agile can be difficult, especially in organizations accustomed to traditional methods. But a gradual approach to this new methodology is warranted: provide Agile training, start with pilot projects, and celebrate early wins to build confidence.

 

Final takeaways

Agile programming is more than just a methodology — it’s a mindset that promotes adaptability, efficiency, and collaboration. By embracing Agile, teams can deliver high-quality software faster while continuously improving their processes. Whether you’re a startup or an enterprise, adopting Agile can lead to better productivity and customer satisfaction.

 

Interested in learning more?

Download our new white paper that provides a detailed case study on implementing Agile and Scrum for SAS programming in clinical development.

Download your copy today!
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Peggy Schrammel

VP, FSP North America

Peggy Schrammel is VP, FSP North America, at Cytel. She brings 25+ years of experience in the CRO arena, having held global senior roles in both Operations and Account Management.

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