The year 2025 promises to be an exciting one for pharmaceutical innovation, with an array of new therapies set to reshape the treatment landscape. From oncology to rare diseases, the industry is preparing to deliver innovative solutions across a diverse range of indications. In oncology, Summit Therapeutics’ ivonescimab will target non-small cell lung cancer and later breast cancer, while Daiichi Sankyo’s Enhertu expands its label to treat additional tumor types. In immunology, Johnson & Johnson’s Tremfya seeks approvals for Crohn’s disease and ulcerative colitis, with Amgen’s Uplizna pursuing indications for myasthenia gravis. Novo Nordisk’s CagriSema could redefine obesity treatment with potential weight loss exceeding 20%, while innovations in rare diseases include Elamipretide for Barth syndrome and Upstaza for AADC deficiency, addressing critical unmet needs. While all these projected launches represent significant scientific innovations, the road to successful commercialization in Germany requires more than scientific breakthroughs — it demands a strategic and tailored communication plan.

One of the most critical challenges in the German market is launch timing. Regulatory approvals are often uncertain, leaving companies working in a state of “near readiness.” Materials must be prepared to an advanced stage but remain flexible enough to adapt to last-minute changes. Furthermore, with the EU HTA reforms having entered into force on January 11, 2025, pharmaceutical companies are facing new dynamics in the evaluation of innovative therapies, which aim to streamline market access and improve patient outcomes.

Here, we’ll explore how to effectively prepare communication materials for a launch, breaking down the key phases.

Phase I – Pre-Launch

Step 1: Crafting your story and defining the USP

Each successful pharmaceutical launch starts with a clear story and a well-defined unique selling proposition (USP). With clinical trial data already available at this stage, your team can craft a compelling narrative that resonates with both healthcare professionals (HCPs) and patients.

Defining the USP
The USP should highlight the product’s most valuable features. This is not necessarily an efficacy-related feature. For instance, simplicity in application can be a game-changer. Imagine transitioning from a treatment requiring three daily doses — often missed due to the complexity of adherence — to a single daily dose. This change not only improves adherence but also may enhance therapeutic outcomes and patient satisfaction.

Storytelling: Making your message stick
People remember stories far better than plain facts, a phenomenon known as story bias. Structuring your information as a narrative helps HCPs quickly grasp and retain the key message. Emotional appeal plays a significant role in this, making the message more memorable when tied to an impactful story.

The key elements of an effective story include:

1. Starting point: The current situation or challenge (e.g., low adherence with multi-dose regimens).
2. Conflict or problem: The pain points or unmet needs.
3. Tension: The stakes involved, creating a sense of urgency.
4. Solution: How the new product resolves these issues (e.g., simpler dosing leading to better outcomes).

Aligning story and message
While the story provides a narrative, your core message delivers the USP explicitly. It’s crucial to distill this into one clear, written statement that connects seamlessly with the story. For example:

• Message: A once-daily treatment improves adherence and satisfaction.
• Story: From the struggles of managing multiple daily doses to the simplicity and success of once-daily therapy.

By aligning the message with the story, you ensure that HCPs not only understand but also remember your product’s unique benefits.

Step 2: Building a robust publication strategy

A well-planned publication strategy is essential for maintaining momentum and ensuring that your product remains top-of-mind for HCPs over time. This phase requires strategic foresight, long-term planning, and alignment with your product’s unique story and USP.

Phases of a publication strategy
To create a cohesive and impactful presence, publications should be carefully timed to align with the product lifecycle:

1. Pivotal study results: Highlight key clinical data that underpin your product’s value.
2. Launch period: Release data and materials that support your key messages during the launch.
3. Congress presentations: Leverage scientific platforms to amplify your findings.
4. Case studies: Showcase how your product is used in everyday work of HCPs and what patients it is for.
5. Review articles: Provide comprehensive overviews of the treatment landscape and background for your product.
6. Non-interventional studies: Showcase real-world data to support effectiveness, safety and treatment adherence.

Long-term planning: Staying in focus
It’s vital to map out your publication strategy well in advance, especially before launch. The goal is to keep your product in the spotlight by regularly contributing to relevant discussions in the medical community. Some activities, such as planning a non-interventional study, require significant lead time and early involvement of HCPs in study design.

Setting the right topics
Your topics should align with your product’s story and USP. For example:

• Mechanism of action: Highlight novel mechanisms that set your product apart.
• Efficacy: Clinically relevant subgroup analyses or responder analyses can highlight efficacy outcomes further.
• Safety and tolerability: An important topic for clinical practice. HCPs should know what to expect and how to manage.
• Quality of life: Shift the conversation towards patient-centric outcomes.

A strong thematic focus helps positioning your product within the broader medical narrative. For instance, if the USP emphasizes improved quality of life rather than a survival advantage, ensure that this topic is prominently discussed in key publications, congress presentations, and continuing medical education (CMEs) programs.

Phase II – Launch

Step 1: Making the pivotal study known

The results from the pivotal study form the backbone of any pharmaceutical launch. They provide the data that underscores your product’s value, making it essential to disseminate the findings effectively and strategically to the medical community. Alongside this, preparing impactful launch materials ensures your sales and medical teams are equipped to engage with HCPs confidently and consistently.

Your pivotal study data needs to reach the right audience through the right channels:

• KOL presentations: Engage trusted key opinion leaders (KOLs) to present findings at relevant conferences and symposiums, lending credibility and reach to your data.
• Reprints and special issues: Distribute reprints of the study in medical journals or as targeted mailings.
• Secondary publications: Collaborate with thought leaders to craft secondary articles to set the right topics (see above).

Step 2: Prepare essential materials

These materials act as a starting point for your field force, giving them something tangible to distribute and discuss during their initial interactions with HCPs. When creating materials, prioritize clarity and relevance.

1. Quick-access materials
   • One-pagers: Compact, easy-to-read documents summarizing key product benefits and clinical data. These are ideal for quick reference and can be prepared early in the launch process.
   • Handout cards: Provide practical guidance, such as managing side effects or linking to a landing page via QR codes.
2. Core materials
   • Detail aids: Ensure these materials support the product’s story and facilitate a natural conversational flow. Include elements like case studies to make the narrative relatable and impactful.
   • Slide decks: Develop a comprehensive slide kit that serves as the foundation for all other materials, from sales presentations to training content.
   • Conversation guides/objection handlers: Provide structured guidance for handling objections and addressing key questions effectively.

By focusing on these priorities, your materials will resonate effectively with HCPs, reinforcing your product’s value and fostering trust.

Step 3: Preparing the sales force

A well-prepared sales force is critical for effectively communicating a product’s value to HCPs. Training should not only provide in-depth knowledge of the product but also focus on presenting the benefits in a way that resonates with the physician’s daily practice and patient care priorities.

Comprehensive training: Thinking like an HCP
When training your sales team, it’s essential to adopt the HCP’s perspective. What matters most to the physician? Tailor the messaging to address the specific needs and interests of their role, practice, and patients.

• Key questions for training:
  • What challenges does this product address for HCPs?
  • How does it make their workflow for patient treatment smoother?
  • What benefits can it provide to patients under their care?

To refine these messages and ensure relevance, consider engaging an Advisory Board of HCPs to provide insights during the preparation phase.

Translating product benefits into practical advantages
Effective communication bridges the gap between product features and the everyday concerns of HCPs and patients. Consider the following perspectives:

• For the physician: How does the product improve treatment efficacy, patient outcomes, or time efficiency?
• For practice staff: Does it simplify workflows or improve patient management?
• For patients: What’s the tangible impact on their quality of life, adherence, or treatment experience?

For example, if the product offers once-daily dosing, the message for physicians could emphasize improved adherence and better clinical outcomes, while for patients, it could highlight ease of use and reduced daily burden.

Addressing side effects: A crucial focus
While side effects may not be the most engaging topic from a marketing perspective, they are highly relevant to HCPs. Addressing this aspect thoughtfully can establish trust and confidence:

• Side effect management: Provide clear, actionable guidance on identifying and managing common side effects.
• Adherence strategies: Equip HCPs with tools to counsel patients effectively, helping them stay on treatment despite potential challenges.

By emphasizing practical solutions to these concerns, your sales team can engage in meaningful, trust-building conversations with HCPs.

Phase III – Post-Launch

The launch may mark the beginning of your product’s presence in the market, but the post-launch phase is where sustained engagement solidifies success. This stage is about expanding your material offerings, deepening HCP and patient interactions, and leveraging diverse communication channels to maximize impact.

Step 1: Expanding materials and strengthening communication channels

As the product becomes established, adding resources tailored to both HCPs and patients ensures continued interest and adoption:

• Brochures and patient materials: Create informative materials that HCPs can hand directly to patients, addressing key concerns and enhancing their understanding of the treatment.
• Case studies: Develop clinical case studies to showcase real-world application and outcomes, helping HCPs connect evidence to practice.
• Interactive study content: Transform pivotal study data into interactive formats, such as e-learning modules, to engage users more effectively.
• Digital content: Enhance digital engagement with webcasts, podcasts, web content, and CME programs.

Step 2: Leveraging multiple communication channels

Different HCPs prefer different modes of communication. To make your message stick, it’s crucial to diversify your channels and formats:

• Written content: Journals, brochures, and patient handouts for in-depth reading.
• Audio content: Podcasts and narrated case studies for convenience and accessibility.
• Visual content: Infographics, videos, and interactive slide decks to illustrate key points vividly.
• Interactive engagements: Webinars, webcasts, and live Q&A sessions to foster real-time interaction and dialogue.

By continuously expanding resources and strategically using diverse communication formats, your post-launch strategy can maintain momentum, deepen engagement, and ensure long-term success.

Final takeaways: Strategic communication for a successful launch

Launching a pharmaceutical product requires meticulous planning, strategic storytelling, and continuous engagement. From pre-launch preparation to post-launch expansion, every phase is an opportunity to address the needs of healthcare professionals, establish your product’s value, and create lasting impact.

By aligning your messaging with the unique demands of the German market, utilizing multi-channel communication strategies, and addressing the priorities of both HCPs and patients, you can ensure a successful launch and a strong market presence.

Interested in learning more? Watch our recent webinar “Guide to Successful G-BA Consultations: Practical Tips for Market Access Professionals”:

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